Description of the Method

It is an unsupervised NMF-based (non-negative matrix factorizationn) deconvolution.

Feature selection

No feature selection

Deconvolution

The deconvolution is based on Non-negative Matrix Factorization (NMF) called by the NMF::nmf function, with the parameter method = "snmf/r".

Results

The program returns an estimated proportion matrix and the corresponding estimated cell-type specific profiles matrix.

Descriptors

Omics_type = trancriptome and methylome

Cancer_type = all

Method_type = unsupervised

Cell_type = all